The Relationship between LvCTL1 and WSSV Replication

QIU Wei; CHEN Yihong

doi:10.6054/j.jscnun.2020094

Journal of South China Normal University (Natural Science Edition) > 2020 > 52(6): 52-56. > DOI: 10.6054/j.jscnun.2020094

QIU Wei, CHEN Yihong. The Relationship between LvCTL1 and WSSV Replication[J]. Journal of South China Normal University (Natural Science Edition), 2020, 52(6): 52-56. DOI: 10.6054/j.jscnun.2020094

Citation:

QIU Wei, CHEN Yihong. The Relationship between LvCTL1 and WSSV Replication[J]. Journal of South China Normal University (Natural Science Edition), 2020, 52(6): 52-56. DOI: 10.6054/j.jscnun.2020094

Citation:

QIU Wei, CHEN Yihong. The Relationship between LvCTL1 and WSSV Replication[J]. Journal of South China Normal University (Natural Science Edition), 2020, 52(6): 52-56. DOI: 10.6054/j.jscnun.2020094

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The Relationship between LvCTL1 and WSSV Replication

QIU Wei¹,
CHEN Yihong^2, ,

1.
School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, China
2.
School of Life Sciences, South China Normal University, Guangzhou 510631, China

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Received Date: August 23, 2020
Available Online: January 04, 2021

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Abstract

Abstract

C-type lectin (CTL) is an important innate immune factor that plays an important role in the immune defense of prawns. The gene expression was detected with relative quantitative PCR, the virus number was detected with absolute quantitative PCR, and the number of infected cells was detected with histology analysis. The data showed that the expression of LvCTL1 was significantly upregulated with WSSV challenge; the expression of WSSV envelope protein VP28, virus loads and the number of infected cells of stomach epithelium in LvCTL1 knockdown prawns upon WSSV infection were significantly higher than those under the dsEGFP control. These results indicated that LvCTL1 expression was significantly activated with WSSV challenge and played a role in WSSV replication inhibition.
- C-type lectin,
- WSSV,
- Litopenaeus vannamei

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References

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