天然抗氧化剂L-肌肽的合成研究[J]. 华南师范大学学报(自然科学版), 2007, 1(2).
引用本文: 天然抗氧化剂L-肌肽的合成研究[J]. 华南师范大学学报(自然科学版), 2007, 1(2).
Synthesis of L-Carnosine[J]. Journal of South China Normal University (Natural Science Edition), 2007, 1(2).
Citation: Synthesis of L-Carnosine[J]. Journal of South China Normal University (Natural Science Edition), 2007, 1(2).

天然抗氧化剂L-肌肽的合成研究

Synthesis of L-Carnosine

  • 摘要: 以L-组氨酸和氰乙酸乙酯为原料,经氨解、氢化两步反应,以62.7%的总产率合成了目标物L-肌肽,并对目标物的结构采用IR、1H NMR、13C NMR和EI-MS进行了表征. 此合成工艺简单,操作方便,生产成本低,具有较好的工业应用前景.

     

    Abstract: L-Carnosine was synthesized in a higher yield from L-histidine and ethyl cyanoacetate through two steps: ammonolysis, hydrogenation, the total yield is 62.7%. The product was confirmed by IR、1H NMR、13C NMR and EI-MS. The production technology was simple and operation was easy, and its cost was low, so it can be considered of good prospect for industrial application.

     

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