Abstract: Bi₂WO₆ with visible light response were prepared by a one-step hydrothermal method. The materials were characterized and analyzed by SEM, TEM, XRD and UV-Vis DRS. Reactive substances were characterized by ESR technique. Photocatalytic performance was tested with Clofibric Acid as the target pollutant, and the effects of pollutant concentration, catalyst dosage, current strength, solution pH, anion and Humic Acid presence on the photocatalytic performance were investigated. The experiments showed that the Bi₂WO₆ material had good catalytic effect on Clofibric Acid under visible light and achieved the best degradation under the conditions of pollutant concentration of 10 mg/L, catalyst dosage of 60 mg(0.6 g/L), current intensity of 20 A, initial solution pH of 5.0 and without Humic Acid. h⁺ and ·OH were the main active oxidizing substances of the reaction, and the photodegradation rate of the material decreased only less than 2% after five cycles.