通过检测热碱解前后污泥理化指标变化，以及不同曝气量（Qb=0.5 、2 L/min）和不同固体停留时间（solids retention time，SRT）（10、20 d）条件下好氧消化（conventional aerobic digestion，CAD）和热碱解-好氧消化（Thermal-Alkaline Pretreatment-conventional aerobic digestion，taCAD）2种工艺常规指标和抗性基因（ARGs）的变化，文章评价了热碱解-好氧消化（Thermal-Alkaline Pretreatment-conventional aerobic digestion，taCAD）工艺处理剩余污泥的效能，并初步评价了其生态风险. 结果表明：在pH=11，T=70℃，t=1 h的热碱解条件下，污泥胞内物质大量释放，热碱解混合物中（sCOD）、（多糖）、（蛋白质）等可达到原污泥的数10倍. 当CAD工艺SRT=10 d时，热碱解的VS去除率分别提高113.9%（Qb=0.5 L/min），160.5%（Qb=2L/min），TCOD去除率分别提高和234.6%（Qb=0.5 L/min）、83.3%（Qb=2 L/min）的. taCAD处理后（NH3-N）明显低于CAD的. 热碱解会使得后续CAD反应器中（sCOD）和（TP）上升. 减小曝气量、延长SRT的CAD过程有利于ARGs的削减，热碱解可导致CAD中部分ARGs回升. 相关性分析和微生物群落结构分析结果表明：CAD中的ARGs传播途径以基因水平转移（HGT）途径为主. 文章在初步评价taCAD工艺生态风险的同时，也为其后续污泥处置方式的选择提供理论依据.
In order to evaluate the efficiency of the Thermal-Alkaline Pretreatment-conventional aerobic digestion (taCAD) process and evaluate its ecological risk initially, the changes of physicochemical characteristics of sludge before and after thermal alkaline hydrolysis(TAH), as well as the changes of conventional indicators and antibiotic resistance genes(ARGs) of conventional aerobic digestion (CAD) and Thermal-alkaline hydrolysis-conventional aerobic digestion(taCAD) under different aeration rates (Qb=0.5，2 L/min) and solids retention time (SRT) (10 , 20 d) were tested . The results showed that under the conditions of TAH at pH=11, T=70℃ and t=1 h, a large amount of intracellular substances were released from sludge cells, and the content of sCOD, polysaccharides and protein in supernatant could reach Tens of times the number of raw sludge. When the SRT of CAD was 10 d, TAH could increase the VS removal rate by 113.9%(Qb=0.5 L/min), 160.5%(Qb=2 L/min) and TCOD removal rate by 234.6%(Qb=0.5 L/min), 83.3%(Qb=2 L/min). TAH could also significantly improve the oxidation capacity of NH3-N of CAD system, but it would increase the sCOD and TP in reactor. Reducing the amount of aeration, extending the SRT of CAD was beneficial to the reduction of ARGs, while TAH could lead to the rebound of part of ARGs in CAD. Correlation analysis and microbial community structure analysis showed that the ARGs transmission pathway in CAD system was mainly based on gene horizontal transfer (HGT) . This study preliminarily evaluated the ecological environment risk of taCAD and provided a theoretical basis for the selection of subsequent sludge disposal methods.