新型气相毛细管柱的制备及其色谱分离

贾成俊, 颜霞, 范军, 郑盛润, 章伟光

贾成俊, 颜霞, 范军, 郑盛润, 章伟光. 新型气相毛细管柱的制备及其色谱分离[J]. 华南师范大学学报(自然科学版), 2014, 46(6): 80-84.
引用本文: 贾成俊, 颜霞, 范军, 郑盛润, 章伟光. 新型气相毛细管柱的制备及其色谱分离[J]. 华南师范大学学报(自然科学版), 2014, 46(6): 80-84.
Preparation and Separation Behaviors of New Gas Phase Capillary Columns with β-Cyclodextrin Derivatives[J]. Journal of South China Normal University (Natural Science Edition), 2014, 46(6): 80-84.
Citation: Preparation and Separation Behaviors of New Gas Phase Capillary Columns with β-Cyclodextrin Derivatives[J]. Journal of South China Normal University (Natural Science Edition), 2014, 46(6): 80-84.

新型气相毛细管柱的制备及其色谱分离

基金项目: 

功能化介孔硅胶手性分离材料的制备与拆分性能;气相色谱毛细管手性柱的研制及在药物、石化分析中的应用

详细信息
    通讯作者:

    贾成俊

Preparation and Separation Behaviors of New Gas Phase Capillary Columns with β-Cyclodextrin Derivatives

  • 摘要: 将羟丙基--环糊精(HP--CD)静态涂覆在毛细管内壁得到一种新的气相毛细管柱,以正十二烷为溶质测得该色谱柱的理论塔板数为2337/m,与涂覆七-(2,6-O-二戊基-3- O-三氟乙酰基)--环糊精(DP-TFA--CD)的毛细管柱柱效相近;在这两种毛细管柱上对对5种二取代苯系化合物(如硝基甲苯、硝基氯苯、二氯苯、二甲苯和苯二酸二甲酯)的位置异构体进行分离研究。结果表明,它们对邻位/对位、间位/对位取代苯系化合物表现较好的分离能力,在HP--CD柱上,二氯苯异构体的分离因子分别为1.28和1.13,比DP-TFA--CD柱的分离效果好。
    Abstract: A new capillary column was prepared by statically coating hydroxypropyl--cyclodextrin (HP--CD) onto inner surface of fused capillary and its theoretical plate number is measured to be 2337 /m according to the literature method, which is close to a commercial gas phase capillary column coated with heptakis-(2, 6-O-dipentyl-3-O-trifluoro acetyl)--cyclodextrin (denoted as DP-TFA--CD). Separations of some benzene positional isomers, namely, nitrotoluene, nitrochlorobenzen, dichlorobenzene, xylene, and dimethyl phthalate, were investigated on these two capillary columns in gas chromatography. The HP--CD and DP-TFA--CD columns show good separation abilities toward five selected analytes. Separation factors for dichlorobenzene on the HP--CD column are 1.28 and 1.13, respectively, which are better than the other.
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出版历程
  • 收稿日期:  2013-12-17
  • 修回日期:  2014-02-07
  • 刊出日期:  2014-11-24

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