Abstract: A wireless wearable pulse-monitoring system was designed based on PVDF fibers derived from the electrospinning process. The good adhesion of the flexible fibers to the skin surface and their high sensitivity helped to detect the pulse vibration at radial artery's epidermis. The pulse signal was sent to the computer in real time through Bluetooth transmission to realize remote and long-term monitoring of the pulse. The results show that the sensitivity of the fiber structure-derived sensor is almost twice that of the piezoelectric film without fiber structure. Compared with commercial clamp-type oximetry, the average error of the new system is less than 3%, which suggests potential applicability in monitoring the physiological signals of the human body.