Abstract: The asymptotic behavior of an SIRS epidemic model containing information intervention and vaccination has been studied. The results indicate that the basic reproduction number ℜ₀ is the threshold of disease persistence and extinction. If ℜ₀ < 1, the system has an disease-free equilibrium which is globally asymptotically stable, while if ℜ₀>1, there exists an epidemic equilibrium which is globally asymptotically stable. At last, some numerical exam-ples are given to illustrate the results.